Eyeballs hurt covid vaccine8/27/2023 All terms were used as words in titles, abstracts, and keywords. We used the following keywords for searching the databases: ((“2019-nCoV” OR “nCoV-19” OR “nCoV-2019” OR “SARS-CoV-2” OR “SARS-CoV2” OR “SARSCoV2” OR “SARS2” OR “COVID” OR “coronavirus” OR “coronavirus disease 2019” OR “severe acute respiratory syndrome”) vaccine) AND (“eye” OR “ocular” OR “oculopathy” OR “oculomotor” OR “intraocular” OR “extraocular” OR “ophthalmic” OR “vision” OR “orbit” OR “cornea” OR “conjunctiva” OR “retina” OR “sclera” OR “vitreous” OR “diplopia” OR “metamorphopsia” OR “visual” OR “optic”)). To comprehensively identify the ocular manifestations of COVID-19 vaccination, we systematically searched three databases, including Embase, Medline (Ovid), and Cochrane Central for studies on related topics. In this study, we aimed to review all reported ocular side effects of the available COVID-19 vaccines. Several adverse events, including ocular manifestations, have been reported after vaccination. BNT162b2 (Pfizer/BioNTech, Mainz, Germany) and mRNA-1273 (Moderna, Cambridge, MA, USA) belong to the category of lipid nanoparticle (LNP)-formulated mRNA COVID-19 vaccines, while ChAdO×1 (University of Oxford/AstraZeneca, Oxford, UK) and (Johnson & Johnson/Janssen, New Brunswick, NJ, USA) belong to the category of adenovirus vector COVID-19 vaccines. Currently, EMA has approved four vaccines that are protective against SARS-CoV-2. The European Medicines Agency (EMA) and the US Food and Drug Administration have approved emergency use authorization for several COVID-19 vaccines before the completion of their clinical trials. The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulted in an unprecedented pandemic worldwide. Although the incidence rate of ocular symptoms is considerably lower in the vaccinated subjects than in COVID-19 patients, physicians should be aware of the possible associations between COVID-19 vaccines and ocular symptoms for the early diagnosis and treatment of vision problems or life-threatening complications. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses may be responsible. Ocular manifestations after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. Two case-control studies/retrospective cohort studies, one cross-sectional study, three case series, sixteen case reports, two images, and seven letters were included. A systemic search was performed on 22 August 2021 through Embase, Medline, and Cochrane Library for publications on ocular manifestations after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to the eye, after receiving COVID-19 vaccination. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019.
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |